The ASCB Post staff brings you the latest news about science, advocacy, discovery, innovation, research and funding.


Generational Warfare Erupts in Comments on NIH’s “Gentle Into That Good Night” Grants

Is it a tempest in an Erlenmeyer flask, a diabolical plot against senior researchers, or a cost efficient way to pass along productive inquiries? An NIH proposal for a new funding mechanism to help senior investigators transition into retirement has set off an intergenerational fracas  … Read more

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Rescuing the Golgi Puts Brakes on Alzheimer’s Progression

Alzheimer’s disease (AD) progresses inside the brain in a rising storm of cellular chaos as deposits of the toxic protein, amyloid-beta (Aβ), overwhelm neurons. An apparent side effect of accumulating Aβ in neurons is the fragmentation of the Golgi apparatus, the part of the cell  … Read more

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New “Alzheimer’s in a Dish” Model Uses Skin Cells to Make Induced Neurons That Express Amyloid-beta and Tau

The search for a living laboratory model of human neurons in the grip of Alzheimer’s disease (AD)—the so-called “Alzheimer’s in a dish”—has a new candidate. In work presented at the ASCB/IFCB meeting in Philadelphia, Håkan Toresson and colleagues at Lund University in Sweden report success  … Read more

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The 2014 ASCB Kaluza Prize sponsored by Beckman-Coulter

The Kaluza Prizes honors the best in graduate student bioscience research. The American Society for Cell Biology (ASCB), in collaboration with Beckman Coulter Life Sciences, gave cash awards of $5,000 to Josie Clowney, $3,000 to Eunyong Park, and $1,000 to Jiaxi Wu.

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Drone Footage of the ASCB2014 Exhibit Hall

Check out our first ever drone footage of the Exhibit Hall at #ASCB2014

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Gravity—It’s the Law Even for Cells

Everybody knows that cells are microscopic, but why? Why aren’t cells bigger? The average animal cell is 10 microns across and the traditional explanation has been cells are the perfect size because if they were any bigger it would be difficult to get enough nutrients  … Read more

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Blood Brain Barrier on a Chip Could Stand in for Children in Pediatric Brain Research

In the human brain, the BBB is not the Better Business Bureau but the blood brain barrier and the BBB is serious business in human physiology. The human BBB separates circulating blood from the central nervous system, thus protecting the brain from many infections and  … Read more

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An Unholy Alliance—Colon Cancer Cells in situ Co-Opt Fibroblasts in Surrounding Tissue to Break Out

It means cancer “in place” but a carcinoma “in situ” often does not want to keep its place. Standing between a cancer cell in situ and the surrounding tissue of fibroblasts and extracellular matrix is the basement membrane, a thin sheet of fibers that normally  … Read more

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Screening for Matrix Effect in Leukemia Subtypes Could Sharpen Chemotherapy Targeting

Location, location, location goes the old real estate proverb but cancer also responds to its neighborhood, particularly in the physical surroundings of bone marrow cells where human myeloid leukemias arise and where, according to two Harvard bioengineers, stiffness in the surrounding extracellular matrix (ECM) can  … Read more

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Complementary Light Switchable Proteins and Superresolution Reveal Moving Protein Complexes in Live Cells at Single Molecule Level

Cells are restless. They move during embryogenesis, tissue repair, regeneration, chemotaxis. Even in disease, tumor metastasis, cells get around. To do this, they have to keep reorganizing their cytoskeleton, removing pieces from one end of a microtubule and adding them to the front, like a  … Read more

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