The ASCB Post staff brings you the latest news about science, advocacy, discovery, innovation, research and funding.


Cell News—Membrane lipids: Sphingolipid metabolism regulates Toll-Like Receptor signals

Köberlin et al. investigated the regulatory role of membrane lipid composition in Toll-Like Receptor (TLR) signaling. They found that sphingolipid metabolism regulates TLR signaling, trafficking, and cytokine release, and that annotated lipid networks can predict TLR responses in patient cells. Published in Cell.

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Cell News—Evolutionary biology: Same gene, different mutation drives pigeon and dove feathered crowns

Charles Darwin loved pigeons. Much of his evidence for variation as a driver in evolutionary change cited in “On the Origin of Species” is based on his first-hand knowledge of Victorian “fancy” pigeon breeding. Of course, Darwin lacked all knowledge of modern genetics but now  … Read more

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Cell News—Membrane trafficking: Sorting signal found for chloride channel

de la Fuente-Ortega et al. identified the dileucine motif sorting signal for the basolateral chloride channel ClC-2. They also found that it is sorted by clathrin adaptor AP-1. Published in MBoC.

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Cell News—Plants: Arabidopsis growth control complex similar to human DREAM/dREAM

Kobayashi et. al. identify activator and repressor complexes that regulate mitotic target genes and organ growth in Arabidopsis thaliana. They found that the repressor complex is similar to the DREAM/dREAM complexes in human and fly. Published in EMBO.

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CRISPR and other Mindboggling Techniques of 21st Century Biology

Can’t get enough CRISPR? Nature writer Heidi Ledford’s feature on the possible ethical and legal problems lurking in the transformative gene editing technology led off a special Nature section earlier this month. Then there was Andrew Pollack’s profile of Jennifer Doudna, University of California, Berkeley.  … Read more

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Our People—Shaw for Bassler’s Quorum Sensing, Hinchcliffe Picked for FRED Mentorship, Scott ‘Premium’ for Hayflick, Immigrants’ Prize for Walter

Bassler Wins Shaw for Quorum Sensing   Princeton’s Bonnie Bassler, a Howard Hughes Medical Institute (HHMI) investigator and ASCB member, has been awarded the Shaw Prize in Life Science and Medicine for her role in the discovery of quorum sensing in bacteria. Quorum sensing is  … Read more

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Rock Talker Leaving NIH for New USDA Research Effort, Walter Koroshetz named Director of the National Institute of Neurological Disorders and Stroke

Sally Rockey, who was NIH’s Delphic Oracle with her inside viewpoint “Rock Talk” blog, is leaving the NIH Office of Extramural Research to become the Director of the new Foundation for Food and Agriculture Research at the U.S. Department of Agriculture (USDA). The foundation is  … Read more

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ASCB Grad Students Get the Vote

For the first time, ASCB graduate student members will be allowed to vote in future Society elections. In a unanimous vote this morning at its spring meeting in Bethesda, the ASCB Council agree to change the Society’s by-laws and give voting rights to all current  … Read more

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Our People—NIH Picks Blau for Challenge Finals, Science Teachers Honor Ken Miller

Stanford’s Helen Blau Finalist in NIH “Follow That Cell” Funding Challenge Helen Blau, professor at Stanford University and ASCB member, is one of 16 finalists in the NIH’s Follow That Cell challenge. The $500,000 challenge asked investigators to generate new tools for analyzing single cells  … Read more

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Generational Warfare Erupts in Comments on NIH’s “Gentle Into That Good Night” Grants

Is it a tempest in an Erlenmeyer flask, a diabolical plot against senior researchers, or a cost efficient way to pass along productive inquiries? An NIH proposal for a new funding mechanism to help senior investigators transition into retirement has set off an intergenerational fracas  … Read more

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