PAIR-UP Advanced Imaging Workshop for Black Imaging Scientists

October 3rd – 6th, 2023 | Time: 9AM – 5PM EDT | Location: Michigan State University, East Lansing, Michigan

The PAIR-UP Advanced Imaging Workshop is designed to provide training in the following major areas:

1.Workshop participants will have the opportunity to learn: principles of operation and hands-on knowledge of using in vivo imaging modalities including PET/MRI, microCT, optical imaging and MPI.

2. Participants will leave the workshop with firsthand knowledge of how to obtain in vivo imaging data using each of the instruments. Image acquisition, image processing, and analysis.

Who Should Attend?
• Principal Investigator (PAIR-UP Black Imaging scientist or
personnel from the PI’s lab)
• Postdoctoral Fellow (in lab of PAIR-UP PI)

Imaging Equipment Used:

PET/MRI: Biospec 70/30 (Bruker) – a 7T MRI with an insert for simultaneous acquisition of PET images.

Magnetic Particle Imaging (MPI): Magnetic Insight Momentum – specifically detects superparamagnetic iron oxide particles in mice and can be used for cell tracking or early cancer detection.

microCT: QuantumGX (Perkin Elmer) – suitable for all analytical CT applications and features cardiac gated imaging, an adjustable bore size that enables imaging of a wide range of species up to rabbits in size, and an energy range of 20-90 kV.

Optical Imaging – Bioluminescence and Fluorescence: IVIS Spectrum (Perkin Elmer) – this pre-clinical imaging system combines high-sensitivity in vivo imaging of fluorescence and bioluminescence, high throughput (5 mice) with 23 cm field of view and high resolution (to 20 microns) with 3.9 cm field of view.

Learning Objectives:

  1. Understand and explain the principles of operation of each imaging modality;
  2. Learn about contrast agents for in vivo applications (early detection, cell tracking, biodistribution etc.);
  3. Familiarize with the workflow for preparing biological samples for specific imaging modalities;
  4. Interpret, understand and analyze the data and assess potential artifacts;
  5. Perform animal preparation for in vivo imaging for each modality;
  6. Determine which instrument is most suitable to acquire data to answer a specific biological question.

Featured Instructors:

Organizer, Dr. Anna Moore (Director, Precision Health Program, Assistant Dean, College of Human Medicine and Professor of Radiology, Department of Radiology)

Dr. Erik Shapiro (Professor of Radiology, Department of Radiology, Associate Chair of Research)

Dr. Kurt Zinn (Professor of Radiology, Department of Radiology, Director of Radiopharmacy)

Dr. Ashley Makela (Postdoctoral Fellow, Institute for Quantitative Health Science and Engineering)

Dr. Kendell Pawelec (Assistant Professor, Department of Radiology)

Dr. Chris Contag (Director, Institute for Quantitative Health Science and Engineering (@MSUIQ), Inaugural Chair and Professor, Department of Biomedical Engineering and Professor, Department of Microbiology & Molecular Genetics)

Cost To Attend: The workshop is free to accepted applicants.

Application Deadline: Friday, August 25th, 2023