Cosponsored by the National Cancer Institute and American Society for Cell Biology

National Institutes of Health, Natcher Auditorium, Building 45, Bethesda, MD 20892
Abstract/Poster Submission Deadline: March 12 Extended to Wednesday, March 14.

Meeting OverviewScheduleRegistrationPoster AbstractsCancellation PolicyHousing/TravelSupport Options

Meeting Overview

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Organizing Committee:
Michael Graham Espey,
PhD, Program Director, Cancer Cell Biology Branch, Division of Cancer Biology, National Cancer Institute
J. Randy Knowlton, PhD, 
Program Director, Structural Biology Branch, Division of Cancer Biology, National Cancer Institute
Derek K. Toomre, PhD, 
Associate Professor of Cell Biology, Director of the ‘CINEMA’ Laboratory, (Cellular Imaging using New Microscopy Approaches), Yale University School of Medicine
Yantian Zhang, PhD,
 Program Director, Cancer Imaging Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute

Substantial improvements in resolution and quantitative imaging techniques have enabled basic discovery research for monitoring of dynamic biological processes at the cellular to subcellular scale. The purpose of this strategic workshop is to identify the needs, opportunities and impediments in applying new and transformational imaging technologies to address fundamental cancer cell biology questions. The workshop will be interdisciplinary by design, at the interface between biophysics, biomedical engineering and cancer cell biology. Over the course of two days, numerous nano-to-micro scale imaging modalities, such as super-resolution nanoscopy, hyperspectral imaging, cryo-EM, photoacoustic microscopy, single molecule tracking, and 3D force imaging, will be featured to develop a multiscale perspective of cancer. Active discussions will prompt participants to examine the interactions that link molecular structure, cellular organization-composition and (dys)function in cancer processes. The outcome of the workshop will be a more cohesive strategy for bringing in high quality imaging approaches to examine basic cancer biology.


Meeting Schedule

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Thursday, April 5, 2018
Natcher Auditorium, Building 45, Bethesda, MD

8:00 am Meeting Arrival and Registration
8:45-9:00 am Organizing Committee Welcome and Meeting Goals
Michael Graham Espey, PhD, National Cancer Institute
J. Randy Knowlton, PhD, National Cancer Institute
Derek K. Toomre, PhD, Yale University School of Medicine
Yantian Zhang, PhD, National Cancer Institute
9:00-9:45 am Keynote: Multiphoton Intravital Imaging at Single Cell Resolution Reveals the Mechanism of Cancer Cell Dissemination and Metastasis
John S. Condeelis, PhD, Albert Einstein College of Medicine
9:45 am-12:30 pm Session 1: Potential of Superresolution Nanoscopy in Cancer
Moderator: Daniel A. Fletcher, PhD, University of California at Berkeley
9:45-10:10 am New Methods in 3D Spatial-Temporal Organelle Dynamics. Joerg Bewersdorf, PhD, Yale University
10:10-10:35 am Nanoscale Cancer Cell Nuclear Architecture. Yang Liu, PhD, University of Pittsburgh
10:35-10:50 am Break (on your own)
10:50-11:15 am Single Molecule-Resolved Kras Regulation. Jay Groves, PhD, University of California at Berkeley
11:15-11:40 am Tracking EGFR Dynamics, TSNUAMI Imaging. Tim Hsin-Chih Yeh, PhD, University of Texas at Austin
11:40 am-12:05 pm Single Molecule Imaging of Transcription in Cancer. Warren R. Zipfel, PhD, Cornell University
12:05-12:30 pm Panel Discussion 1
12:30-1:15 pm Lunch (on your own)
1:15-4:20 pm Session 2: Cancer Cells in Context
Moderator: Jodi Nunnari, PhD, University of California at Davis
1:15-1:40 pm Unraveling Cancer Cell Nanoarchitecture through Multiscale Imaging. Dorit Hanein, PhD, Sanford Burnham Research Institute
1:40-2:05 pm Cancer Cell Morphodynamics. Reto Fiolka, PhD, University of Texas Southwestern Medical Center
2:05-2:30 pm Cancer Cell Force Spectrum Microscopy. Ming Guo, PhD, Massachusetts Institute of Technology
2:30-2:45pm Break (on your own)
2:45-3:10 pm Spatial Distribution of p53 and Mitochondria; Geared for Invasion. Michelle Digman, PhD, University of California at Irvine
3:10-3:35 pm Mito-Dynamics: Bridging Super-res. to Cancer Cell Behavior, Jerry E. Chipuk, PhD, Mount Sinai, Icahn School of Medicine
3:35-4:00 pm Photonic Crystal Enhanced Microscopy of the Cellular Microenvironment. Brian Cunningham, PhD, University of Illinois at Urbana-Champaign
4:00-4:20 pm Panel Discussion 2
4:30-5:30 pm Poster Session 1 (Atrium Level)
5:30 pm Adjourn Day 1


Friday, April 6, 2018
Natcher Auditorium, Building 45, Bethesda, MD

8:00 am Meeting Arrival and Registration
8:45-9:00 am Reprise Day 1
Michael Graham Espey, PhD, National Cancer Institute
J. Randy Knowlton, PhD, National Cancer Institute
Derek K. Toomre, PhD, Yale University School of Medicine
Yantian Zhang, PhD, National Cancer Institute
9:00-11:00 am Session 3: The Right Probe for the Right Cancer Question
Moderator: Jianghong Rao, PhD, Stanford University
9:00-9:25 am Peeling the Lid on Living Circuits. Klaus Hahn, PhD, University of North Carolina
9:25-9:50 pm Intracellular pH Dynamics Enabling Multiple Cancer Behaviors. Diane Barber, PhD, University of California at San Francisco
9:50-10:10 am Break (on your own)
10:10-10:35 am Imaging Redox and Zinc Dynamics in Cancer Cells. Hui-wang Ai, PhD, University of Virginia School of Medicine
10:35-11:00 am Panel Discussion 3
11:00 am-12:00 pm Poster Session 2 (Atrium Level)
12:00-1:00 pm Lunch (on your own)
1:00-3:00 pm Session 4: Imaging Tumor System Dynamics
Moderator:  John Hancock, MB, BChir, PhD, University of Texas Health
1:00-1:25 pm Zebra fish as a Model of Cancer Stem Cell Dynamics. David Langenau, PhD, Massachusetts General Hospital & Harvard University
1:25-1:50 pm Label-Free Spectroscopic Imaging of Structural Alterations in Cancer Progression. Lev Perelman, PhD, Harvard University
1:50-2:15 pm Community Dynamics in Cancer Organoids. Melissa Skala, PhD, University of Wisconsin
2:15-2:40 pm Emergent and Collective Behaviors of Invasion. Peter Friedl, MD, PhD, Radboud University Nijmegen
2:40-3:00 pm Panel Discussion 4
3:00-3:15 pm Wrap-Up and Adjourn


*subject to change


Registration is open and will close on March 28, 2018, or when the meeting is full, whichever comes first. Please register below. 

ASCB Members receive a steeply discounted registration rate for this two-day meeting. Please see rates below:

Registration Category*
Registration Rate
ASCB Regular Member $150
Regular Nonmember $315
ASCB Postdoctoral Member $115
Postdoctoral Nonmember $205
Government Employee $0

*Please Note: This meeting is not intended for Graduate Students or Undergraduate Students. We strongly encourage you to join the ASCB if you are not already a member for substantial savings. Click here to join or renew your dues, or for more information about ASCB membership.

How to Submit an Abstract to Present a Poster at the Workshop- deadline extended to March 14

Not Yet Registered:

The abstracts for potential poster presentation at the workshop are collected during the registration process. There is not addition fee to submit an abstract but you will need to register for the workshop in order to submit an abstract. Visit the registration tab above, or click here to register and submit your abstract. All abstracts that are relevant to the meeting will be ACCEPTED. The deadline for Abstract Submission for Poster Presentation has been extended to Wednesday, March 14. 

During the registration process, you will be asked if you would like to submit an abstract for poster presentation. If you select, “yes”, you will be asked to enter the following fields:

  • Abstract Title (200 characters max)
  • Abstract Authors (400 characters max)
  • Abstract Body (2,500 characters max)

You will fill out your abstract information, and continue with the registration process as normal.

If you are already registered and want to go back to submit an abstract, please contact the ASCB at

Cancellation Policy

Meeting registration is nontransferable. Meeting registration is nonrefundable after March 22, 2018. The ASCB will honor requests for refunds if they are in writing and are received by the ASCB no later than March 22, 2018. Please note that cancellations are subject to a processing fee of $40 for regular members and nonmembers and $30 for postdoc members and nonmembers. No refunds will be issued for requests received after March 22. Please send a request for cancellation to or The cancellation fees do not apply to government employees.

Housing & Travel


The ASCB has negotiated a small number of hotel rooms at the DoubleTree by Hilton Hotel in Bethesda at a discounted rate. The hotel is approximately 0.7 miles from the Natcher Conference Center, about a 15 minute walk. No shuttles will be provided by ASCB or NCI. Hotel information:

DoubleTree by Hilton Hotel Bethesda
8120 Wisconsin Ave, Bethesda, MD 20814
(301) 652-2000

Discounted rates from $209 USD/night plus taxes for the nights of April 4, 5, and 6.

Deadline to reserve a room is March 5th. The special room rate will be available until March 5, 2018, or until the group block is sold-out, whichever comes first. 

TRAVEL (information has been adapted from:
Getting to the NIH and the Natcher Conference Center:

Please visit: for information on how to get to the NIH.

Click here for information on Campus Access and Security.

Click here for NIH Campus Maps.

Support Opportunities

The ASCB is not actively seeking supporters for this meeting. However, if you wish to support a coffee break, snack break, or lunch, please contact Alison Harris, Director of Meetings, at 301-347-9346 or