MBoC Perspective blog posts are a series of articles that explore forward-looking ideas, emerging trends, and provocative questions shaping the future of cell biology. Molecular Biology of the Cell (MBoC) is ASCB’s office scientific journal.
Author: Shreya S. Bellampalli, Vikram Joshi, Gennadiy Fonar & Arthur Beyder
Monitoring Editor: Keith Kozminski
Abstract
Enteroendocrine cells (EECs) of the gastrointestinal epithelium serve as a unique model to investigate how cyclic AMP (cAMP) and calcium signaling pathways intersect to regulate hormone and neurotransmitter release. This perspective synthesizes recent advances in understanding Ca²⁺ and cAMP dynamics, method‑driven insights into their convergence, and implications for gastrointestinal function, metabolism, and disease.
Figure: Sertoli cells lacking Sel1L support normal testis development and sperm production..
About the Author:
This post was collaboratively written by several ASCB staff members.