Please enjoy our quarterly highlighted articles from Molecular Biology of the Cell (MBoC), which were noted by reviewers and editors to be of particular interest and significance.

Yeast ribosomal protein Rpl32 modulates ribosome biogenesis, ribosome stability and the cell cycle
Authors: Stephen M. Doris, Elizabeth S. Noblin, Raphyel Rosby, and Susan A. Gerbi

Distinct signaling mechanisms and proteome phenotypes are elicited by compartment-specific genetic defects of copper homeostasis
Authors: Alicia R. Lane, Nadia Gonzalez, Avanti Gokhale, Stephanie A. Zlatic, Brooke M. Allen, Noah E. Scher, Anne M. Roberts, Duc M. Duong, Blaine R. Roberts, Alysia D. Vrailas-Mortimer, Erica Werner, and Victor Faundez

Molecular and cellular determinants of human iron overload cardiomyopathy
Authors: Sayli S. Modak, Lina Greenberg, W. Tom Stump, Akiva E. Greenberg, Nathaniel Huebsch, and Michael J. Greenberg

Sphingolipid regulation by yeast Mdm1 supports adaptive remodeling of the methionine transporter Mup1
Authors: Daniel Adebayo, Eseiwi Obaseki, Kashvi Vasudeva, Marwa Aboumourad, Scott Miller, Anne Ostermeyer-Fay, Daniel Canals, Xun Bao, Jing Li, and Hanaa Hariri

APC^Cdh1-mediated degradation of Cdh1 is necessary for faithful meiosis in Saccharomyces cerevisiae
Authors: Denis Ostapenko and Mark J. Solomon

RanBP2-dependent SUMOylation of G3BP2 inhibits formation, and promotes disassembly, of stress granules
Authors: Yifan E. Wang, Javid Guliyev, Sean S.J. Ihn, Gaelen Moore, Fermisk Saleh, Hyun O. Lee, and Alexander F. Palazzo

Divisome and elongasome organisation in the genome-reduced obligate intracellular bacterium Orientia tsutsugamushi
Authors: Suthida Chuenklin, Elizabeth Harris, Owen Somhorst, and Jeanne Salje

A GUV-based assay to reconstitute membrane tethering in vitro
Authors: Devika Andhare and Michael J. Ragusa

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