MBoC Publishes New Articles on Biomolecular Condensates

ASCB’s scientific journal, Molecular Biology of the Cell (MBoC) is pleased to present its special collection on Biomolecular Condensates.

Lead Editors

Amy Gladfelter, Duke University
Jeffrey B. Woodruff, UT Southwestern Medical Center
Huaiying Zhang, Carnegie Mellon

Articles

• The dark side of flourescent protein tagging–the impact of protein tags on biomolecular condensation
  Authors: Edoardo Fatti, Sarah Khawaja, and Karsten Weis
• Zelda is dispensable for Drosophila melanogaster histone gene regulation
  Authors: Tommy O’Haren, Tsutomu Aoki, and Leila E. Rieder
• Optical characterization of molecular interaction strength in protein condensates
  Authors: Timon Beck, Lize-Mari van der Linden, Wade M. Borcherds, Kyoohyun Kim, Raimund Schlüßler, Paul Müller, Titus M. Franzmann, Conrad Möckel, Ruchi Goswami, Mark Leaver, Tanja Mittag, Simon Alberti, and Jochen Guck
• Diffusion within the synaptonemal complex can account for signal transduction along meiotic chromosomes
  Authors: Lexy von Diezmann, Chloe Bristow, and Ofer Rog
• G3BP isoforms differentially affect stress granule assembly and gene expression during cellular stress
  Authors: José M. Liboy-Lugo, Carla A. Espinoza, Jessica Sheu-Gruttadauria, Jesslyn E. Park, Albert Xu, Ziad Jowhar, Angela L. Gao, José A. Carmona-Negrón, Torsten Wittmann, Natalia Jura, and Stephen N. Floor
• Med13 is required for efficient P-body recruitment and autophagic degradation of Edc3 following nitrogen starvation
  Authors: Sara E. Hanley, Stephen D. Willis, Brittany Friedson, and Katrina F. Cooper
• The CCT chaperonin and actin modulate the ER and RNA-binding protein condensation during oogenesis and maintain translational repression of maternal mRNA and oocyte quality
  Authors: Mohamed T. Elaswad, Mingze Gao, Victoria E. Tice, Cora G. Bright, Grace M. Thomas, Chloe Munderloh, Nicholas J. Trombley, Christya N. Haddad, Ulysses G. Johnson, Ashley N. Cichon, and Jennifer A. Schisa
• Measurement of solubility product reveals the interplay of oligomerization and self-association for defining condensate formation
  Authors: Aniruddha Chattaraj, Zeynep Baltaci, Steve Chung, Bruce J. Mayer, Leslie M. Loew, and Jonathon A. Ditlev
• Fluorescent protein tags affect the condensation properties of a phase-separating viral protein
  Authors: Ressell J. R. Barkley, Jack C. Crowley, Andrew J. Brodrick, Warren R. Zipfel, and John S. L. Parker
• Interplay of condensation and chromatin binding underlies BRD4 targeting
  Authors: Amy R. Strom, Jorine M. Eeftens, Yury Polyachenko, Claire J. Weaver, Hans-Frederick Watanabe, Dan Bracha, Natalia D. Orlovsky, Chanelle C. Jumper, William M. Jacobs, and Clifford P. Brangwynne
• Buffer choice and pH strongly influence phase separation of SARS-CoV-2 nucleocapsid with RNA
  Authors: Nina C. Kathe, Mihajlo Novakovic, and Frédéric H.-T. Allain
• NAGPKin: Nucleation-andgrowth parameters from the kinetics of protein phase separation
  Authors: Zsuzsa Sárkány, Francisco Figueiredo, Sandra Macedo-Ribeiro, and Pedro M. Martins