ASCB’s Public Information Committee has selected these 14 abstracts in two rounds of parallel peer-screening as “Honor” abstracts to be presented at the 2015 ASCB Annual Meeting in San Diego, December 12-16. PIC screeners voted for abstracts that represented exciting new science with direct relevance to human health or to emerging new approaches to cell biology. The abstracts are listed here by the day they will be presented in San Diego at the ASCB meeting and NOT in ranked order. In addition, PIC picked out six “Best Cell Stories 2015,” marked with asterisks, that will be featured at the meeting.
SUNDAY, DECEMBER 13
* Begum Erdogan – Cancer-associated fibroblasts promote directional migration of cancer cells via parallel organization of the fibronectin matrix
Erdogan1, M. Ao1, B.M. Brewer2, O.E. Franco3,4,5, S.W. Hayward3,4,5, D. Li2, D.J. Webb1,3; 1Biological Sciences, Vanderbilt University, Nashville, TN, 2Mechanical Engineering, Vanderbilt University, Nashville, TN, 3Cancer Biology, Vanderbilt University, Nashville, TN,4Surgery, NorthShore University HealthSystem, Evanston, IL, 5Urologic Surgery, Vanderbilt University, Nashville, TN
Author presents:
Microsymposium 01: Cell Motility and Migration
Microsymposia Room 1
E1
12:05 pm – 12:10 pm
*Selected as a “A Best Cell Story 2015”
B1506: Jintao Liu – Metabolic co-dependence gives rise to collective oscillations within microbial communities
Liu1, A. Prindle1, J. Humphries1, M. Gabalda-Sagarra2, M. Asally3, D.D. Lee1, S. Ly1, J. Garcia-Ojalvo2, G.M. Suel1; 1Division of Biological Sciences, University of California San Diego, La Joalla, CA, 2Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain, 3Warwick Integrative Synthetic Biology Centre, School of Life Sciences, University of Warwick, Coventry, United Kingdom
Author presents:
Systems Biology and Tissue Engineering
Learning Center
B1506/P663
1:30 pm – 3:00 pm
* Micah Webster – Intravital Imaging Reveals Ghost Fibers as Architectural Units Guiding Muscle Progenitors During Skeletal Muscle Regeneration
M.T. Webster1, U. Manor2, J. Lippincott-Schwartz2, C. Fan1; 1Embryology, Carnegie Institution for Science, Baltimore, MD, 2NICHD, National Institutes of Health, Bethesda, MD
Author presents:
Minisymposium 01: Cell Migration in Tissues
Ballroom 20D
M7
6:05 pm – 6:12 pm
MONDAY, DECEMBER 14
Christopher Suarez – Understanding and overcoming ZNF217 induced breast cancer chemoresistance
C.D. Suarez1, L.E. Littlepage1, S.S. Badve2; 1Chemistry and Biochemistry, University of Notre Dame, South Bend, IN, 2Pathology and Laboratory Medicine, Indiana University Purdue University Indianapolis, Indianapolis, IN
Author presents:
Defining Therapeutic Targets and New Therapeutics 2
Learning Center
B1685/P1605
12:00 pm – 1:30 pm
* Pedro Lowenstein – Streams, swirls, and neurospheres: in vivo self-organization of brain tumors revealed by mathematical and biological modeling
P.R. Lowenstein1,2, S. Motsch3, V.A. Yadav1, D. Zamler1, C. Koschmann1, F. Nunez-Aguilera1, A. Calinescu1, N. Kamran1, M. Dzaman1, M.G. Castro1,2; 1Department of Neurosurgery, The University of Michigan, Ann Arbor, MI,2Department of Cell and Developmental Biology, The University of Michigan, Ann Arbor, MI, 3Department of Mathematics and Statistics, Arizona State University , Tempe, AZ
Author presents:
Tumor Invasion and Metastasis 2
Learning Center
B714/P1079
1:30 pm – 3:00 pm
*Selected as a “A Best PIC Cell Story 2015”
* Corrine Kliment – Cytoskeletal and Mitochondrial Genes as New Targets in the Protection of Airway Epithelial Cells Against Cigarette Smoke
C.R. Kliment1,2, Y. Lu3, S.M. Claypool3, R. Sidhaye1, D.N. Robinson2; 1Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, 2Cell Biology, Johns Hopkins University, Baltimore, MD, 3Physiology, Johns Hopkins University, Baltimore, MD
Author Presents:
Defining Therapeutic Targets and New Therapeutics 2
Learning Center
B1682/P1602
1:30 pm – 3:00 pm
*Selected as a “A Best PIC Cell Story 2015”
Xuezhi Zhang – Sentinel cells of the social amoeba Dictyostelium traps and kills bacteria by casting DNA nets
Zhang1, O. Zhuchenko2, K. Adam2, T. Soldati1; 1Department of Biochemistry, University of Geneva, Geneva, Switzerland, 2Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX
Author presents:
Microsymposium 08: The Role of the Cytoskeleton in Disease and Repair
Microsymposia Room 2
E54
12:25 pm – 12:30 pm
* Benjamin Freedman – Modeling Polycystic Kidney Disease Cystogenesis with Genome-Modified Human Pluripotent Stem Cells
B.S. Freedman1,2, T.I. Steinman3, J. Zhou2, J.V. Bonventre2; 1Department of Medicine, Division of Nephrology, University of Washington, Seattle, WA, 2Department of Medicine, Renal Division, Brigham and Womens Hospital/Harvard Medical School, Boston, MA, 3Department of Medicine, Division of Nephrology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA
Author presents:
Microsymposium 08: The Role of the Cytoskeleton in Disease and Repair
Microsymposia Room 2
E55
12:30 pm – 12:35 pm
*Selected as a “A Best PIC Cell Story 2015”
TUESDAY, DECEMBER 15
Kuo-chen Wang – Inhibition of RhoA/ROCK signaling directs human mesenchymal stem cells toward chondrogenesis
Wang1, L. Rizzi De Freitas2, K. Aris3, D.G. Thomas4, J.F. Welter1, T.T. Egelhoff4, H. Baskaran5; 1Biology, Case Western Reserve University, Cleveland, OH, 2Faculdade de Engenharia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil, 3Hathaway Brown School, Shaker Heights, OH, 4Cell and Molecular Medicine, Cleveland Clinic, Cleveland, OH, 5Chemical and Biomolecular Engineering, Case Western Reserve University, Cleveland, OH
Author presents:
Actin and Actin-Associated Proteins 3
Learning Center
B345/P1656,
12:00 pm – 1:30 pm
Gal Haimovich – Cell-to-cell transfer of mRNA via membrane nanotubes
Haimovich1, J.E. Gerst1, R.H. Singer2,3; 1Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel,2Anatomy & Structural Biology, Albert Einstein College of Medicine , Bronx, New-York, NY, 3Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine , Bronx, New-York, NY
Author presents:
Microsymposium 16: Cell Biology of Genetic Information
Microsymposia Room 2
E106
1:30pm – 1:35pm
Peter Ly – Reconstructing Chromothripsis: Inducible Fragmentation and Rearrangement of a Specific Human Chromosome
Ly1,2, L.S. Teitz3,4, D.H. Kim1,2, O. Shoshani1,2, H. Skaletsky3,4, D.C. Page3,4, D. Fachinetti5, D.W. Cleveland1,2; 1Ludwig Institute for Cancer Research, La Jolla, CA, 2Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA,3Department of Biology, Massachusetts Institute of Technology, Cambridge, MA,4Whitehead Institute for Biomedical Research, Cambridge, MA,5Department of Subcellular Structure and Cellular Dynamics, CNRS UMR 144, Institut Curie, Paris, France
Author presents:
Chromosome Organization
Learning Center
B600/P1785
1:30 pm – 3:00 pm
Rebecca Lamason – Intercellular communication pathways are hijacked by bacterial pathogens during cell-to-cell spread
Lamason1, M.D. Welch1; 1MCB, UC Berkeley, Berkeley, CA
Author presents:
Microsymposium 15: Membrane Regulation and Signaling
Microsymposia Room 1
E102
1:45 pm – 1:50 pm
* Sarah Elkin – A systematic analysis of cancer cells reveals heterogeneous changes in their endocytic activities
S.R. Elkin1, N. Bendris1, C.R. Reis1, Y. Zhou2, Y. Xie2, K.E. Huffman3, J.D. Minna3,4,5, S.L. Schmid1; 1Cell Biology, UT Southwestern, Dallas, TX, 2Clinical Science, Quantitative Biomedical Research Center, UT Southwestern, Dallas, TX, 3The Hamon Center for Therapeutic Oncology Research, UT Southwestern, Dallas, TX,4Internal Medicine, UT Southwestern, Dallas, TX, 5Pharmacology, UT Southwestern, Dallas, TX
Author presents:
Endocytic Trafficking 2
Learning Center
B804/P1953
1:30 pm – 3:00 pm
*Selected as a “A Best PIC Cell Story 2015”
WEDNESDAY, DECEMBER 16
Mary Teruel – A circadian code for fat cell differentiation
Bahrami-Nejad1, M.L. Zhao1, K. Tkach1, S. von Schie1, M.N. Teruel1; 1Chemical and Systems Biology, Stanford University, Stanford, CA
Author presents:
Minisymposium 22: Mammalian Cell Signaling
Room 32B
M188
9:35 am – 9:55 am
