David Drubin, Editor-in-Chief of Molecular Biology of the Cell (MBoC), and Valerie Weaver, an Associate Editor of MBoC, have announced plans to publish a second special issue on “Forces On and Within Cells.” The last special issue was published in August 2018 (https://www.molbiolcell.org/toc/mboc/29/16). Weaver, of the University of California, San Francisco, will again serve as lead Issue Editor.


Among the topics within the scope of the special issue on Forces On and Within Cells are:

  • Force-generating machines
  • Force-detecting mechanisms
  • Force regulation of cell and tissue phenotype:
    • Receptor signaling
    • Stem cell differentiation
    • Cell migration
    • Cell cycle regulation
    • Cell survival
    • Nuclear architecture
    • Chromatin structure and gene expression
  • Force regulation of tissue development and homeostasis
  • Perturbed force in disease:
    • Cardiovascular disease
    • Cancer
    • Degenerative diseases
  • Measuring force at the subcellular, cellular, and tissue level
  • Manipulating force at the subcellular, cellular, and tissue level
  • Modeling force at the single cell and tissue level


The issue will be published in summer 2019. Authors are encouraged to submit manuscripts by February 1, 2019, to allow time for them to be reviewed and revised by the deadline for the special issue. Manuscripts may be submitted at www.mbcpapers.org. Questions about the issue should be directed to David Drubin at mboc@ascb.org.