Molecular Biology of the Cell (MBoC) Editor-in-Chief David Drubin has announced plans to publish a Special Issue on an important emerging area of cell biology, the Cell Biology of Stem Cells. Yukiko Yamashita, Diane Barber, TerryLechler, Jason Spence, and David Traver will serve as Issue Editors.While much attention has focused on the great promise of stem cells for human health applications through tissue repair and disease modeling, stem cells are also proving to be attractive subjects for discovery of biological mechanisms. The abilities to produce many different cell types isogenetically from the same parent stem cells and to produce organoids of many tissue types make stem cells uniquely valuable for studies of cell biological mechanisms.
Among the topics to be included in the Special Issue are:
- Cell biology of stem cells and cells derived from them, including studies of:
- Cellular architecture and physiology
- Stem cell niches
- Differentiation mechanisms, including:
- Cellular mechanisms for reprogramming cell architecture
- Cellular mechanisms for reprogramming cell physiology
- Genomic and proteomic studies of differentiation
- Methods for studying and differentiating stem cells and producing organoids
- Disease models with an emphasis on cell biological aspects
- Organoids for analyzing cell physiology and collective cell behavior in a tissue-like setting
The Special Issue will be published in fall 2018. Authors are encouraged to submit research Articles and Brief Reports by May 15, 2018, and Perspectives (essays) by June 15, 2018, to allow them to be reviewed and revised by the deadline for the Special Issue.