Undergraduate Program

If you would like to participate in this program and you are an Undergraduate Student who are not registered for the meeting, please come directly to Room 204BC with your student ID.

Where the Cytoplasm Meets the Cell Cortex: How Chance Encounters Build Cells and Scientists

Amy S. Gladfelter, Dartmouth College

Saturday, December 11, 2010, 3:30-4:30 pm
Philadelphia Convention Center, Room 204BC
Philadelphia, PA     

Why do scientists who want to learn more about cells study fungus? Fungal systems are amenable to genetics, can be grown in large quantities, and are less complicated than mammalian systems. This presentation will focus on the path that led Dr. Gladfelter to her current study of two research questions: 1) How do cells build a dynamic but persistent septin cytoskeletal structure at the cell cortex? 2) How do nuclei establish functional neighborhoods of distinct cytoplasm in their vicinity and carry these neighborhoods with them as they migrate through cells? Gladfelter will show how live cell imaging can be combined with statistical modeling and molecular genetics to understand how cells establish distinct functional domains of the cell cortex and the cytoplasm.

Attention Teachers: To prepare your students for this subject, direct them to the following articles:
Free: Asynchronous nuclear division cycles in multinucleated cells. Gladfelter AS, Hungerbuehler AK, Philippsen P. J Cell Biol. 2006 Jan 30;172(3):347-62.PMID: 16449188, and Regulation of distinct septin rings in a single cell by Elm1p and Gin4p kinases. DeMay BS, Meseroll RA, Occhipinti P, Gladfelter AS. Mol Biol Cell. 2009 Apr;20(8):2311-26. Epub 2009 Feb 18.PMID: 19225152
Reviews for a Fee: Nuclear anarchy: asynchronous mitosis in multinucleated fungal hyphae. Gladfelter AS. Curr Opin Microbiol. 2006 Dec;9(6):547-52. Epub 2006 Oct 11. Review.PMID: 17045513 and Dancing genomes: fungal nuclear positioning. Gladfelter A, Berman J. Nat Rev Microbiol. 2009 Dec;7(12):875-86. Epub 2009 Nov 9. Review.PMID: 19898490

A 30-minute talk will be followed by Q&A. An undergraduate poster presentation and light refreshments will be held from 4:45 pm-5:45 pm.

Attendees are invited to attend the Keynote Symposium, "Improving Cancer Chemotherapy: How Can a Basic Scientist Contribute," by Timothy Mitchison from the Harvard Medical School, at 6:00pm.
There is no cost to attend this program; however, pre–registration is requested.

If you are not registered for the entire meeting, badges may be picked up in Room 204BC for access to the Keynote session. Be sure to have your student ID with you or you may be denied access.

If you are interested in presenting a poster, please submit an abstract and check the box in step 2.

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