Genes and Cells that Determine the Lifespan of C. elegans

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Genes and Cells that Determine the Lifespan of C. elegans
Cynthia Kenyon, May 2007
Department of Biochemistry and Biophysics, University of California, San Francisco

Lecture Overview
Once it was thought that aging was just a random and haphazard process. Instead, the rate of aging turns out to be subject to regulation by transcription factors that respond to hormones and other signals. In the nematode C. elegans, in which many key discoveries about aging were first made, the aging process is subject to regulation by food intake, sensory perception, and signals from the reproductive system. Changing genes and cells that affect aging can lengthen lifespan by six fold, and can also delay age-related disease, such as the growth of tumors.
Part 2: The Regulation of Aging by Signals from the Reproductive System, and, also, a Link Between Aging and Tumor Growth (37:16)

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Format Descriptions
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Part 1: An Evolutionarily-Conserved Regulatory System for Aging (42:46)

Speaker Bio    Related Articles

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Lecture Overview Once it was thought that aging was just a random and haphazard process. Instead, the rate of aging turns out to be subject to regulation by transcription factors that respond to hormones and other signals. In the nematode C. elegans, in which many key discoveries about aging were first made, the aging process is subject to regulation by food intake, sensory perception, and signals from the reproductive system. Changing genes and cells that affect aging can lengthen lifespan by six fold, and can also delay age-related disease, such as the growth of tumors.	Part 2: The Regulation of Aging by Signals from the Reproductive System, and, also, a Link Between Aging and Tumor Growth (37:16) Click image above to start seminar in 320x240 format Click here to view in larger 640x480 format* QuickTime 7 Required 640x480 System Requirements (there may be a few seconds delay before seminars start) Downloads in alternative formats:* (To Save, Right Click a link below and select "Save Target/Link As") QuickTime (70mb) MP4 (436mb) iPod/iPhone Video (436mb) Format Descriptions Download Accelerator/Resume Broken Downloads Software
Part 1: An Evolutionarily-Conserved Regulatory System for Aging (42:46) Speaker Bio Related Articles