It isn't your imagination. The recent ups and downs in biomedical research funding have made for turbulent times in academic laboratories across the US. Jennifer Couzin-Frankel points out in her overview article to an imaginatively reported "News Focus" section last week in Science on the work force and funding crisis in biomedical science that the NIH budget doubled between 1998 and 2003 from around $14 billion to $27 billion but remained essentially flat for the next five years. The 2009 federal stimulus package created a bump in spending of an additional $10.4 billion but the "regular" NIH budget continued to lose altitude as inflation ate away at the actual value of flat funding. Then came last year's heart-stopping federal shutdown and the sickening 5% across the board sequester nose dive. The net result is that the number of R01 principal investigators (PI) has remained virtually static over the last 13 years: NIH funded 20,458 PIs in 2000 and 21,511 PIs in 2013.
There is this awesome technology site called The Verge. How awesome, we can barely tell you although we can reveal a recent The Verge top story: "'Captain America 3' to hit theaters on May 6th, 2016." Save the date. What makes The Verge so additionally awesome, according to the New York Times, is that The Verge belongs to Vox Media, the General Motors conglomerate of the New Digital Media Age. "Vox Takes the Melding of Journalism and Technology to a New Level," says the Times. (Our "snark" meter is broken. Is that headline ironic or puff?)
Nearly every cell in your body is releasing microscopic bubbles that contain tiny messages to other cells in your body. The bubbles are so small that if a cell were the size of the Empire State Building, the vesicles would be the size of teenage couriers, running to deliver messages to neighboring buildings in the organism of Manhattan. But now there's evidence that at least in worms, these little bubbles, called extracellular vesicles (ECVs), can leave the cells of the Manhattan Island worm to deliver messages to cells in the Brooklyn worm. The first of these external messages to be discovered turns out to be a love note.
It's been nearly 14 years since the primary cilium pushed its way into cell biology's center ring with the discovery that this "irrelevant" vestigial organelle was connected to a common and fatal human disorder, polycystic kidney disease (PKD). In the years since, a long list of diseases and disorders have been classified as ciliopathies while the primary cilium currently has 2,347 citations on PubMed.