The name "Sonic hedgehog" may conjure up images of Sega's blue videogame character, tumbling across a screen and collecting gold rings, but its namesake, the human gene Sonic hedgehog, encodes a protein (SHH) whose role in the body is anything but light entertainment.
If you were playing with an app on your phone, you would have missed it. Earlier today, the Senate Labor, Health and Human Services, Education Appropriations Subcommittee approved the FY14 Departments of Labor, Health & Human Services, and Education appropriations bill without amendment and by voice vote. The bill, which is notable for its funding for the U.S. National Institutes of Health (NIH), includes $30.9 billion for the NIH, which is $1.6 billion more than the NIH's FY13 budget, after sequestration.
Under a microscope in Ghana, deadly pathogens look beautiful. Little squiggles of green and blue highlight the cell nuclei of trypanosomes, the protozoa responsible for African sleeping sickness. For the past two weeks, 26 West African students learned skills and techniques that will help them conduct research on these and other infectious pathogens. The courses took place June 17- June 29, 2013, at the University of Ghana, a few miles outside Accra.
Cholera is changing the human genome, according to research published in Science Translational Medicine on Wednesday. The investigators scanned the genomes of individuals living in the Ganges Delta of Bangladesh and West Bengal in India, where cholera is prevalent. ScienceNow and the New York Times report that the researchers found 305 regions of the genome with changes due to cholera, evidence that natural selection made its mark on the genes over the past 5,000 to 30,000 years.