Like a kid hovering over an ant with a magnifying glass, you can easily fry a worm with a microscope. But if you could do it without zapping the subjects, long exposure imaging would be immensely helpful for studying a cell process like development in a living Caenorhabditis elegans embryo. In a pair of just published papers—one in Nature Biotechnology yesterday and another in Nature Methods on October 6—Hari Shroff, tenure-track investigator at the NIH, unveiled a pair of new microscopes that offer an alternative solution to the problem of light-blasted subjects.

Thursday, 10 October 2013 00:00

Open-Access—The Bad and The Good

Written by

Grace Groovy of the International Journal of Cancer and Tumor would be happy to publish your nonsensical data, Science Magazine news reporter John Bohannon discovered. But that journal wasn't the exception. In a 15-month investigation, Bohannon concocted a bogus paper that he fed into a program that randomly generated bogus variations from bogus researchers at various bogus institutions which he then submitted to 304 open-access journals.

A senior researcher who can't get an answer from a shutdown NIH about a proposed clinical trial on a neurodegenerative disease, a Nobel Prize-winning scientist who fears that a generation of innovators will be lost, and a young investigator wearied at the lab by endless funding cuts and frustrated at home by the halt to promising research into a genetic disorder that affects her daughter

Two longtime ASCB members, Randy Schekman of the University of California, Berkeley, and James Rothman of Yale University, have won the 2013 Nobel Prize in Physiology or Medicine for their discoveries of how molecules move through the cell in vesicles and fuse to target membranes in a process known as "trafficking."

submissions

COMPASS Blog