In a move that will reverberate through the NIH extramural community, the NIH announced Friday afternoon how they intend to deal with the massive number of grant applications that were submitted in the days before and during the 16-day government shutdown.

At 12:25 am this morning, President Obama signed legislation ending the 2013 federal fiscal standoff and opening the government after a 16-day shutdown. Minutes later, the Office of Personnel Management sent out an email notifying federal employees that they "are expected to return for work on their next regularly scheduled work day."

There's only one place this weekend where you could crochet proteins, make a laser phonograph, crowd source a science fraud detector, and build a machine that sorts candy by color (a flow confectionometer?). Anyone with an interest in science and a playful streak can sign up to join a two day "science hacker" community in Boston this weekend at Harvard Northwest Building for free (thanks to sponsors like the ASCB), contributing to projects or coming up with their own.

Like a kid hovering over an ant with a magnifying glass, you can easily fry a worm with a microscope. But if you could do it without zapping the subjects, long exposure imaging would be immensely helpful for studying a cell process like development in a living Caenorhabditis elegans embryo. In a pair of just published papers—one in Nature Biotechnology yesterday and another in Nature Methods on October 6—Hari Shroff, tenure-track investigator at the NIH, unveiled a pair of new microscopes that offer an alternative solution to the problem of light-blasted subjects.