2000 ASCB Annual Meeting Press Book - page 2

Richard Hynes, President
Jean Schwarzbauer, Program Chair
Dean Sheppard, Local Arrangements Chair
Elizabeth Hay, 40th Anniversary Chair
The ASCB: 40 Years Leading the Revolution in Cell Biology
Saturday, December 9, 6:00 p.m.
J. Michael Bishop, Michael S. Brown, Joseph L. Goldstein,
Harold E. Varmus
Sunday, December 10
The Mechanism of Protein Synthesis (8:00–9:30 a.m.)
Alan Hinnebusch, Harry F. Noller, Jr., Nahum Sonenberg
Novel Dimensions of Cell Motility (10:30–12:00 noon)
Marie-France Carlier, Thomas M. Roberts, H. Lee Sweeney
Monday, December 11
Chromosome Dynamics (8:00–9:30 a.m.)
Douglas E. Koshland, Victoria Lundblad, Daphne Preuss
Determination of Left-Right Asymmetry (10:30–12:00 noon)
Daniel Constam, Nobutaka Hirokawa, Elizabeth Robertson
Tuesday, December 12
Pathogen Recognition and Host Defense (8:00–9:30 a.m.)
Barbara Baker, Pamela Bjorkman, Ruslan M. Medzhitov
Cellular Organization at the Synapse (10:30–12:00 noon)
Mary Kennedy, Joshua R. Sanes, Morgan Sheng
Wednesday, December 13
Biological Clocks (8:00–9:30 a.m.)
Steve Kay, Ann Rougvie, Joseph S. Takahashi
Chemical Approaches to Biological Problems
(10:30–12:00 noon)
Daniel E. Kahne, Jeff Kelly, Laura Kiessling
(3:30 p.m.-5:45 p.m.)
Sunday, December 10
Checkpoint regulatory proteins
Angelika Amon, Sally Kornbluth
Chromatin modification and nuclear organization
Sarah C.R. Elgin, Sharon Y. Roth
Cytoskeletal machinery and dynamics
Frank B. Gertler, Dorothy A. Schafer
Membrane rafts
Barbara Baird, Frederick R. Maxfield
Novel functions of cadherins and protocadherins
Ulrich Tepass, Tadashi Uemura
Organelle dynamics
Jennifer Lippincott-Schwartz, Janet M. Shaw
December 9-13, 2000
Moscone Convention Center, San Francisco
Monday, December 11
Cell migration and pathfinding
Gian Garriga, Denise Montell
Molecular mechanisms of endocytosis
Frances M. Brodsky, Howard Riezman
Proteoglycans and cell communication
Alan C. Rapraeger, Scott Selleck
Regulation of cytoskeletal motors
Vladimir I. Gelfand, Rong Li
Spindle pole duplication and function
Duane A. Compton, Trisha Davis
Trafficking between nucleus and cytoplasm
Douglass Jane Forbes, Susan Rae Wente
Tuesday, December 12
Cytoskeletal cross-talk and intermediate filaments
Pierre A. Coulombe, Gregg G. Gundersen
Genetics and genomics of cell adhesion
Nicholas H. Brown, Ben Williams
Novel intercellular signaling pathways
Joanne Chory, Roeland Nusse
Post-transcriptional regulation of cellular functions
Victor R. Ambros, Elizabeth R. Gavis
Regulation of membrane traffic by lipids
Jean E. Gruenberg, Wieland B. Huttner
Signal regulation through proteolysis
Paul Polakis, Michael D. Tyers
Wednesday, December 13
Biophysical approaches in cell biology
Steven M. Block, Mimi Koehl
Cell regulation by scaffolding and adaptor proteins
Sharon L. Milgram, John Scott
Centromeres, kinetochores and genomic instability
Pamela B. Meluh, Peter K. Sorger
Extracellular matrix signalling
David D. Schlaepfer, Sheila M. Thomas
Microbial subversion of cellular functions
Pascale Cossart, Jorge Galan
Vesicle docking and fusion
Charles K. Barlowe, Frederick M. Hughson
For more information, contact the ASCB at
(301) 347-9300 or
Northern Elephant Seals, such as those pictured here at Ano Nuevo State Beach and Reserve on the northern California coast, spend the majority of their lives at sea, but
come ashore during the winter months to breed and give birth. The mothers and pups seen here are typically organized into groups known as harems.
Centrosome defects in human tumor-derived cell lines. Immunofluorescence images of a normal cell (bottom left) and a breast tumor cell (right). Pericentrin staining
(yellow) identifies multiple sites for nucleation of microtubules (green); nuclei are blue. The normal cell has a single centrosome capable of nucleating a typical microtubule
array. The tumor cell has a large number of microtubule sites that vary dramatically in size and often lack the characteristic centriole pair found in normal epithelial cell
centrosomes. These atypical microtubulenucleating sites often form the poles of dysfunctional multipolar spindles and thus contribute to chromosome missegregation.
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